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Frisch Ortho Hip and Knee Specialist
  • Rochester
    River District
    Tawas

Publications

Comparison of a Smartphone App to Manual Knee Range of Motion Measurements

Abstract
Digital technology has emerged as a useful tool for preoperative and postoperative patient engagement and for remote patient monitoring. Smartphones are equipped with motion-sensing technology, and apps can be designed which use these features to create a simple method for measuring range of motion. The purpose of this study was to determine the accuracy of digital technology in assessing knee range of motion using a smartphone app, compared to traditional goniometric measurements in an office setting.

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John N. Insall Award: MARCQI’s Pain-Control Optimization Pathway (POP): Impact of Registry Data and Education on Opioid Utilization

Abstract
In 2019, the Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI) recommended an evidence-based opioid pain pathway to participating physicians and hospitals for patients undergoing total joint arthroplasty (TJA). The purpose of this study was to determine if the education could influence and have lasting effects on the prescribing patterns for TJA patients.

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Innovation and Entrepreneurship: Perspectives From Orthopedic Surgery.

Campbell KJ, et al. Orthopedics. 2018.

Abstract
Orthopedic surgeons are tasked with treating complex patients while employing critical surgical skills, clinical knowledge, and new technologies. The constant inundation of information, coupled with hours in the hospital setting, provides unique perspectives on various aspects of how health care is delivered, thereby creating a milieu ripe for innovation. The rigors of an orthopedic career make it challenging for physicians to translate an idea into a great product. Through the authors’ experiences at a tertiary orthopedic practice, they review the process of taking an idea from concept to fruition. [Orthopedics. 201x; xx(x):xx-xx.].

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The utility of botulinum toxin A in the repair of distal biceps tendon ruptures

Abstract
Purpose: The purpose of our study is to report the outcomes and complications in patients who underwent distal biceps tendon repair with the use of Botulinum toxin A (BoNT-A) as an adjunct to surgery.
Methods: A retrospective review of 14 patients who underwent 15 distal biceps tendon repairs was performed. All repaired tendons had their correlating muscle bellies injected intraoperatively with a mixture of 100U of BoNTA and 10 ml of normal saline.

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The Use of MicroRNA Biomarkers to Distinguish Enchondroma from Low Grade Chondrosarcoma.

Abstract
Establishing a definitive diagnosis between benign enchondroma versus low grade chondrosarcoma presents a potential challenge to both clinicians and pathologists. microRNAs (small non-coding RNAs) have proven to be effective biomarkers for the identification of tumors and tumor progression. We present analysis, both array and quantitative PCR, that shows consistently and substantially increased expression of two microRNAs, miRs-181a and -138, in low grade chondrosarcomas compared with enchondromas. The data suggest these microRNAs would provide an analytical distinction between the chondrosarcoma and benign neoplasms that can be performed in formalin fixed paraffin embedded specimens.

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Ultrasound findings in asymptomatic patients with modularmetal on metal total hip arthroplasty

Abstract
Objective: The use of metal-on-metal and modular total hip arthroplasty is associated with potentially serious local and systemic complications. The primary aim of this study was to identify the prevalence of a pseudotumor in asymptomatic patients with a particular metal-on-metal hip prosthesis after aminimum follow-up of 5 years using ultrasound evaluation.
Methods: We prospectively evaluated data collected from 36 asymptomatic patients who underwent implantation of a Profemur Z metal-on-metal total hip arthroplasty from January 2004 to January 2010.

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Single-dose lidocaine spinal anesthesia in hip and knee arthroplasty

Abstract
Background: With the increasing interest in fast recovery and outpatient joint arthroplasty, short-acting local anesthetic agents and minimal narcotic use are preferred. Lidocaine is a fast-onset, short-duration local anesthetic that has been used for many years in spinal anesthesia. However, lidocaine spinal anesthesia has been reported to have a risk of transient neurologic symptoms (TNSs). The purpose of this study is to determine the safety and efficacy of single-dose lidocaine spinal anesthesia in the setting of outpatient joint arthroplasty.
Methods: We performed a prospective study on 50 patients who received lidocaine spinal anesthesia in the setting of outpatient hip and knee arthroplasty. All patients received a single-shot spinal injection, with 2% isobaric lidocaine along with titrated propofol sedation. We evaluated demographic data, length of motor blockage, time to ambulation, time to discharge readiness, patient-reported symptoms of TNS.

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Short Versus Long Cephalomedullary Nails for Pertrochanteric Hip Fracture

Abstract
This study compared patients who underwent treatment with short or long cephalomedullary nails with integrated cephalocervical screws and linear compression. Patients with AO/OTA 31-A2 or A3 pertrochanteric fractures treated with either short (n=72) or long (n=97) InterTAN (Smith & Nephew, Memphis, Tennessee) cephalomedullary nails were reviewed. Information on perioperative measures (estimated blood loss, surgical time, and fluoroscopy time) and postoperative orthopedic complications (infection, implant failure, screw cutout, and periprosthetic femur fracture) was included.

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Rivaroxaban Versus Enoxaparin for Venous Thromboembolism Prophylaxis after Hip and Knee Arthroplasty

Abstract
The oral Factor Xa inhibitor rivaroxaban (Xarelto) has been the pharmacologic agent used for venous thromboembolism(VTE) prophylaxis after primary hip and knee arthroplasty (THA/TKA) at our institution since February 2012. The purpose of our study was to compare rates of VTE and major bleeding between rivaroxaban and our previous protocol of enoxaparin after THA/TKA. A retrospective cohort studywas performed including 2406 consecutive patients at our institution between 1/1/11 and 9/30/13. Patients who did not have unilateral primary THA/TKA or who received other anticoagulants were excluded. Of the 1762 patients included, 1113 patients (63.2%) received enoxaparin and 649 patients (36.8%) received rivaroxaban. This study found no demonstrable differences between these two anticoagulants in rates of VTE, infection, reoperation, transfusion, ormajor bleeding. Therapeutic, Retrospective comparative study, Level III.

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Reconsidering the Affordable Care Act’s Restrictions on Physician-Owned Hospitals

Concerns about financial incentives and increased costs prompted legislation limiting the expansion of physician-owned hospitals in 2010. Supporters of physician-owned hospitals argue that they improve the value of care by improving quality and reducing costs. The purpose of the present study was to determine whether physician-owned and non-physician-owned hospitals differ in terms of costs, outcomes, and patient satisfaction in the setting of total hip arthroplasty (THA) and total knee arthroplasty (TKA).

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Predictors and Complications of Blood Transfusion in Total Hip and Knee Arthroplasty

Abstract
Perioperative patient optimization can minimize the need for blood transfusions in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose of this study was to determine predictors and complications of transfusions. This retrospective review analyzed 1795 patients who underwent primary THA and TKA at our institution between January 2011 and December 2012. Of the 1573 patients ultimately included the rates of transfusion were 9.27% in TKA and 26.6% in THA. Significant predictors for transfusion include: preoperative hemoglobin, age, female gender, body mass index, creatinine, TKA, operating room time, operative blood loss, and intra-operative fluids. The DVT rate was comparable, but deep surgical site infection rate among transfused patients was 2.4% compared to 0.5% in non-transfused patients (P = 0.0065).

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Outcomes of Ankle Fractures in Patients with Uncomplicated Versus Complicated Diabetes

Abstract
Background: Patients with diabetes who sustain an ankle fracture are at increased risk for complications including higher rates of in hospital mortality, in-hospital postoperative complications, length of stay and non-routine discharges. The purpose of this study was to retrospectively compare the complications associated with operatively treated ankle fractures in a group of patients with uncomplicated diabetes versus a group of patients with complicated diabetes. Complicated diabetes was defined as diabetes associated with end organ damage such as peripheral neuropathy, nephropathy and/or PAD. Uncomplicated diabetes was defined as diabetes without any of these associated conditions. Our hypothesis was that patients with uncomplicated diabetes would experience fewer complications than those patients with complicated diabetes.
Methods: We compared the complication rates of ankle fracture repair in 46 patients with complicated diabetes and 59 patients with uncomplicated diabetes and calculated odds ratios (OR) for significant findings. Results: At a mean followup of 21.4 months we found that patients with complicated diabetes had 3.8 times increased risk of overall complications 3.4 times increased risk of a non-infectious complication (malunion, nonunion or Charcot arthropathy) and 5 times higher likelihood of needing revision surgery/arthrodesis when compared to patients with uncomplicated diabetes.

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Intraoperative Periprosthetic Femur Fracture: A Biomechanical Analysis of Cerclage Fixation

Intraoperative periprosthetic femur fracture is a knowncomplication of total hip arthroplasty (THA) and a variety of cerclage systems are available to manage these fractures. The purpose of this study was to examine the in situ biomechanical response of cerclage systems for fixation of periprosthetic femur fractures that occur during cementless THA. We compared cobalt chrome (CoCr) cables, synthetic cables, monofilament wires and hose clamps under axial compressive and torsional loading. Metallic constructs with a positive locking system performed the best, supporting the highest loads with minimal implant subsidence (both axial and angular) after loading. Overall, the CoCr cable and hose clamp had the highest construct stiffness and least reduction in stiffness with increased loading. They were not demonstrably different from each other.

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The stability of dual-taper modular hip implants: a biomechanical analysis examining the effect of impact location on component stability

Abstract
Background: The purpose of this study was to investigate the stability of dual-taper modular implants following impaction forces delivered at varying locations as measured by the distraction forces required to disassemble the components.
Methods: Distraction of the head-neck and neck-stem (NS) tapers of dual-taper modular implants with 0°, 8°, and 15° neck angles were measured utilizing a custom-made distraction fixture attached to a servohydraulic materials test machine. Distraction was measured after hand pressing the components as well as following a simulated firm hammer blow impaction. Impacts to the 0°, 8°, 15° necks were directed axially in line with the neck, 10° anterior, and 10° proximal to the axis of the neck, respectively.

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The Effect of Impact Location on Force Transmission to the Modular Junctions of Dual-Taper Modular Hip Implants

Abstract
Background: The purpose of this study was to investigate the effect that off-axis impaction has on stability of dual-taper modular implants as measured by forces delivered to and transmitted through the head-neck and neck-stem tapers, respectively.
Methods: One hundred forty-four impact tests were performed using 6 different directions: one on-axis and five 10° off-axes. Four different simulations were performed measuring the head-neck only and 3 different neck angulations: 0°, 8°, and 15°. A drop tower impactor delivered both on - and off-axis impaction from a constant height. Load cells positioned in the drop mass and at the head-neck or neck-stem junction measured the impact and joint forces, respectively.

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The Athlete’s Spine - Lumbar Herniated Nucleus Pulposus

Lumbar herniated nucleus pulposus is common among athletes given the physical stresses placed upon the lumbar spine with various athletic activities. Although the natural course is generally favorable with conservative management, there producible success of lumbar discectomy provides itself as an alternative treatment option for the athlete. Both conservative and operative management are associated with quick recovery and return to play. This chapter reviews the natural history of lumbar herniated nucleus pulposus, various treatment modal- ities, and the athlete - specific metrics pertinent to the management of athletes.

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Ewing Sarcoma in the Fifth Metacarpal of an Adult Woman

Abstract
Atypical presentations of Ewing sarcoma (ES) can lead to misdiagnosis and delays in treatment. We present a rare case of ES in the hand of an adult woman who underwent multiple interventions prior to referral to our institution. At 22 months after definitive treatment, the patient remained pleased with the result and had no evidence of recurrence.

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Effect of Body Mass Index on Blood Transfusion in Total Hip and Knee Arthroplasty

Abstract
Perioperative blood management remains a challenge during total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose of this study was to systematically examine the relationship between body mass index (BMI) and perioperative blood transfusion during THA and TKA while attempting to resolve conflicting results in previously published studies. The authors retrospectively evaluated 2399 patients, 896 of whom underwent THA and 1503 of whom underwent TKA. Various outcome variables were assessed for their relationship to BMI, which was stratified using the World Health Organization classification scheme (normal, < 25 kg/m2; overweight, 25-30 kg/m2; obese, >30 kg/m2).

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Do higher-volume hospitals provide better value in revision hip and knee arthroplasty?

We questioned the Centres for Medicare and Medicaid Services (CMS) Inpatient Charge Data and identified 789 hospitals performing a total of 29 580 revision arthroplasties in 2014. Centres were dichotomised into high-volume (performing over 50 revision cases per year) and low-volume. Mean total hospital-specific charges and inpatient payments were obtained from the database and stratified based on Diagnosis Related Group (DRG) codes. Patient satisfaction scores were obtained from the multiyear CMS Hospital Compare database.

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Intraoperative Hypothermia During Surgical Fixation of Hip Fractures

Abstract
Hip fractures are common orthopedic injuries and are associated with significant morbidity/mortality. Intraoperative normothermia is recommended by national guidelines to minimize additional morbidity/mortality, but limited evidence exists regarding hypothermia’s effect on orthopedic patients. The purpose of this study was to determine the incidence of intraoperative hypothermia in patients with operatively treated hip fractures and evaluate its effect on complications and outcomes. Retrospective chart review was performed on clinical records from 1541 consecutive patients who sustained a hip fracture and underwent operative fixation at the authors’ institution between January 2005 and October 2013. A total of 1525 patients were included for analysis, excluding those with injuries requiring additional surgical intervention.

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Intraoperative chlorhexidine irrigation to prevent infection in total hip and knee arthroplasty

Abstract
Background:Surgical site irrigation during total hip (THA) and total knee (TKA) arthroplasty is a routine practice among orthopaedic surgeons to prevent periprosthetic joint infection. The purpose of this study was to evaluate the effect of chlorhexidine gluconate (CHG) irrigation on infection rates following THA and TKA.
Methods: Arthroplasties performed before September 2014 served as controls. THA performed before September 2014 (N ¼ 253) underwent intraoperative irrigation with 0.9% saline followed by a 2-minute soak with < 2% dilute povidone-iodine. TKA (N ¼ 411) patients underwent only intraoperative saline irrigation. After October 2014, all patients (248 TKA and 138 THA) received intraoperative irrigation with 0.9% saline and periodic 0.05% CHG solution followed by a final 1-minute soak in CHG with immediate closure afterward.

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Innovation and Entrepreneurship: Perspectives From Orthopedic Surgery

Abstract
Orthopedic surgeons are tasked with treating complex patients while employing critical surgical skills, clinical knowledge, and new technologies. The constant inundation of information, coupled with hours in the hospital setting, provides unique perspectives on various aspects of how health care is delivered, thereby creating a milieu ripe for innovation. The rigors of an orthopedic career make it challenging for physicians to translate an idea into a great product. Through the authors’ experiences at a tertiary orthopedic practice, they review the process of taking an idea from concept to fruition. [Orthopedics. 201x; xx(x):xx-xx.]

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Improving Value in Total Hip and Knee Arthroplasty: The Role of High Volume Hospitals

Abstract
Background: Recent healthcare reform efforts have focused on improving the quality of total joint replacement care while reducing overall costs. The purpose of this study is to determine if higher volume centers have lower costs and better outcomes than lower volume hospitals.
Methods: We queried the Centers for Medicare and Medicaid Services (CMS) Inpatient Charge Data and identified 2702 hospitals that performed a total of 458,259 primary arthroplasty procedures in 2014. Centers were defined as low (performing < 100 total joint arthroplasty [TJA] per year) or high volume and mean total hospital-specific charges and inpatient payments were obtained. Patient satisfaction scores as well 30-day risk-adjusted complication and readmission scores were obtained from the multiyear CMS Hospital Compare database.

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Hypersensitivity: “Doc, Am I Allergic to My Implant?”

Abstract
There is controversy regarding the clinical significance of metal hypersensitivity in total knee arthroplasty(TKA). Given the current state of the art, metal hypersensitivity, if it exists at all, is a diagnosis of exclusion. Clinical presentation may involve acutaneous response, but current diagnostic methods do not have robust clinical validation and should be used with caution. The two most commonly used tests include cutaneous patch testing and in vitro lymphocyte transformation testing. Initially, conservative management is indicated and other more common causes of asymptomatic total knee replacement should be fully explored. In rare cases, device removal maybe undertaken but this should be considered a last resort. Pre-operative testing prior to a primary total joint replacement may be helpful whenthere′s a patient - reported history of intolerance to jewelry or of an allergic reaction to a prior metal implant, but routine lab screening is not supported by the literature.

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Heterotopic Ossification Prophylaxis After Total Hip Arthroplasty: Randomized Trial of 400 vs 700 cGy

Abstract
Background: Heterotopic ossification (HO) is a known complication following total hip arthroplasty. Radiation is an effective prophylaxis, but an optimal protocol has yet to be determined. We performed a randomized, double-blinded clinical trial in high-risk patients to determine the efficacy of 400 vs 700 cGy doses of radiation.
Methods: One hundred forty-seven patients undergoing total hip arthroplasty and at high risk for HO at an urban medical center were randomized to receive either a single 400 or 700 cGy dose of radiation postoperatively. High risk was defined as a diagnosis of diffuse idiopathic skeletal hyperostosis, hypertrophic osteoarthritis, ankylosing spondylitis, or history of previous HO. Radiation was administered on the first or second postoperative day. A single blinded reviewer graded radiographs taken immediately postoperatively and at a minimum of 6 months postoperatively using the Brooker classification. Progression was defined as an increase in Brooker classification. Operative data including surgical approach, implant fixation, revision surgery, and postoperative range of motion data were also collected.

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Hemispherical and minimally invasive total hip reamers: a biomechanical analysis of use and design

Abstract
Background: The purpose of this study was to determine the accuracy of used and new reamer systems for both hemispherical and minimally invasive (MIS) acetabular reamers.
Methods: New and used hemispherical and MIS acetabular reamers were tested on a computer numerical control machine to ream holes in special machinable wax blocks. Each reamer was tested 3 times in sizes 48 mm through 55 mm.

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Hot off the press this month…new publication

Innovation and Entrepreneurship: Perspectives From Orthopedic Surgery.

Campbell KJ, et al. Orthopedics. 2018.

Abstract
Orthopedic surgeons are tasked with treating complex patients while employing critical surgical skills, clinical knowledge, and new technologies. The constant inundation of information, coupled with hours in the hospital setting, provides unique perspectives on various aspects of how health care is delivered, thereby creating a milieu ripe for innovation. The rigors of an orthopedic career make it challenging for physicians to translate an idea into a great product. Through the authors’ experiences at a tertiary orthopedic practice, they review the process of taking an idea from concept to fruition. [Orthopedics. 201x; xx(x):xx-xx.].

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Book Chapters

  • Frisch NB, and Berger RA. Navigating the limiatations and obstacles of total joint arthroplasty in a free-standing ASC. Outpatient Joint Replacement. Edited by Michael Meneghini. Springer; Anticipated publication 2020.
  • Frisch NB,, Jacobs JJ. Metal Allergy and Management. In “The Adult Knee 2e”, edited by Harry Rubash, Aaron Rosenberg, Robert Barrack, Hany Bediar, Brett Levine, James Huddleston. Wolters Kluwer; 2019.
  • Frisch NB,, Darrith B. Patellofemoral Complications after Total Knee Arthroplasty. In “The Adult Knee 2e”, edited by Harry Rubash, Aaron Rosenberg, Robert Barrack, Hany Bediar, Brett Levine, James Huddleston. Wolters Kluwer; 2019.
  • Frisch NB,, Courtney PM, Shah RP. Health Policy. In “Orthopaedic Knowledge Update 13e”, edited by Javad Parvizi. Wolters Kluwer; 2019.
  • Frisch NB,, Darrith B. Can More than One Compartment be Done? In “Unicompartmental Knee Arthroplasty: Indications, Surgical Techniques and Complications”, edited by Tad Gerlinger. Springer; 2019.
  • McCaslin M, Frisch NB . Partnership, Ancillaries and other Considerations. In "Orthopedic Practice Management: Strategies for Growth and Success", edited by Eric C. Makhni, Melvin C. Makhni, Eric F. Swart and Charles Bush-Joseph. Springer, 2018
  • Frisch NB, Jacobs JJ. Revision for Metal on Metal Failure or Taper Corrosion. In "Surgery of the Hip", edited by Daniel J Berry and Jay R Lieberman: Elsevier, 2018
  • Takamura K, Campbell P, Frisch NB, Jacobs JJ. Biological Responses to Metal Debris, Corrosion Products and Metal Ions. In “Surgery of the Hip”, edited by Daniel J Berry and Jay R Lieberman: Elsevier, 2018.
  • Frisch NB, Darrith B, Della Valle CJ. Previous Knee Sepsis - One Stage. In "Complex Cases in Total Knee Arthroplasty", Chapter 7A, edited by Alfred J. Tria, Giles R. Scuderi, and Fred D. Cushner: Springer, 2017
  • Frisch NB, Jacobs JJ. Hypersensitivity: "Doc, Am I Allergic to My Implant?". In "Seminars in Arthroplasty", edited by A. Seth Greenwald: 2017.
  • Frisch NB, Berger RA. Management of Patellar Tendon Rupture - Extensor Mechanism Allograft. In "Complex Cases in Total Knee Arthroplasty", Chapter 16A, edited by Alfred J. Tria, Giles R. Scuderi, and Fred D. Cushner: Springer, 2017
  • Frisch N, Silverton C. Trochanteric Approaches for Primary THA. In "The Adult Hip, 3rd ed.", Chapter 6, edited by Callaghan J, Beaule P, Clohisy J, Della Valle C, Rosenberg A, and Rubash H., Philadelphia: Wolters Kluwer Health, 2015

Peer Reviewed Journals

  • John N. Insall Award: MARCQI’s Pain-Control Optimization Pathway (POP): Impact of Registry Data and Education on Opioid Utilization

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  • Quantifying Patient Engagement in Total Joint Arthroplasty Using Digital Application-Based Technology

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  • Veterans Undergoing Total Hip and Knee Arthroplasty: 30-day Outcomes as Compared to the General Population

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  • Conversion Total Knee Arthroplasty: Prior Fracture or Osteotomy Around the Knee Leads to Increased Resource Utilization

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  • Dr. Frisch is excited to share his latest publication COVID-19 Impact on Young Arthroplasty Surgeons

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  • Dr. Frisch is excited to share his latest publication Incidence of Pseudotumors in a Dual Modular Stem Construct With and Without Metal-on-Metal Bearing Surface

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  • Frisch NB, Courtney PM, Darrith B, Copeland LA, Gerlinger TL. Veterans Undergoing Total Hip and Knee Arthroplasty: 30-day Outcomes as Compared to the General Population. J Am Acad Orthop Surg. 2020 Jan 30. PMID: 32004175
  • Frisch NB, Rahman TM, Darrith B, Patel I, Silverton CD. Comparison of Harris Hip Scores and Revision Rates in Metal-on-Metal Versus Non-Metal-on-Metal Total Hip Arthroplasty. J AM Acad Orthop Surg 2019 Aug 13. PMID: 31415300
  • Nahm NJ, Frisch NB, Ghacham W, Les CM, Guthreie ST, Charters MA. Radiographic predictors of screw cutout for intertrochanteric fractures treated with cephalomedullary nails. J Surg Orthop Adv 2019,28(2): 115-120. PMID: 31411956
  • Frisch NB, Wessell N, Jildeh TR, Greenstein A, Trent Guthrie S. Early-Stage Chronic Kidney Disease and Hip Fracture Mortality.
  • Darrith B, Frisch NB, Tetreault MW, Fice MP, Culvern CN, Della Valle CJ. Inpatient Versus Outpatient Arthroplasty: A Single-Surgeon, Matched Cohort Analysis of 90-Day Complications.
  • Liu J, Frisch NB, Mehran N, Qatu M, Guthrie ST. Short-term medical complications following short versus long cephalomedullary nails. Orthopedics. 2018 PMID: 30011050
  • Nodzo SR, Frisch NB. The Use of Antibiograms in Orthopedic Surgery. Current Reviews in Musculoskeletal Medicine. 2018 PMID: 29971613
  • Frisch NB, Lynch J, Banglmaier RF, Pourzal R, Silverton CD. Dual Taper Modular Hip Implant: Investigation of 3D Surface Scans for Component Contact, Shape, and Fit. Arthroplasty Today. 2018 PMID: pending
  • Frisch NB, Darrith B, Hansen DC, Wells A, Berger RA. Single-dose lidocaine spinal anesthesia in hip and knee arthroplasty. Arthoplsty Today. 2018. PMID: 29896560
  • Frisch NB, Wessell N, Charters M, Dobson C, Les C, Guthrie T. Hip Fracture Mortality: Differences Between Intertrochanteric and Femoral Neck Fractures. Journal of Surgical Orthopaedic Advances. 2018. PMID: 29762119
  • Courtney MP, Frisch NB, Bohl DD, Della Valle CJ. Improving Value in Total Hip and Knee Arthroplasty: The Role of High Volume Hospitals. Journal of Arthroplasty. 2018 PMID: 28844631
  • Frisch NB, Courtney PM, Darrith B, Della Valle CJ. Do higher-volume hospitals provide better value in revision hip and knee arthroplasty. Bone Joint J, 2017. PMID: 29212684
  • Courtney MP, Darrith B, Bohl DD, Frisch NB, Della Valle CJ. Reconsidering the Affordable Care Act's Restrictions on Physician Owned Hospitals: Analysis of CMS Data on Total Hip and Knee Arthroplasty. JBJS, 2017. PMID: 29135661
  • Frisch NB, Kadri O, Davis JD. Intraoperative Chlorhexidine Gluconate Irrigation during Total Hip and Knee Arthroplasty- Arthroplasty Today. 2017 PMID: 29204500
  • Ross RD, Deng Y, Fang, R, Frisch NB, Jacobs JJ, Sumner DR. Discovery of Biomarkers to Identify Peri-Implant Osteolysis before Radiographic Diagnosis. J Orthop Res. 2018 PMID: 29873110
  • Evans TJ, Frisch NB, Gibson G, Mott MP, Parsons TW. Validation of a Rat Model for Analyzing MicroRNA in Chondrosarcoma. J Musculoskelet Res. 2018. PMID: pending
  • Frisch NB, Wessell NM, Taliaferro K, VanHolsbeeck M, Silverton CD. Ultrasound Findings in Asymptomatic Patients with Dual-Taper Modular THA - Skeletal Radiology. 2017. PMID: 28204856
  • Campbell KJ, Louie PK, Khorsand DK, Frisch NB, Gerlinger TL, Levine BR. Innovation and Entrepreneurship: Perspectives from Orthopaedic Surgery. Orthopedics, 2017. PMID: 29658978
  • Khalil LS, Keller RA, Mehran N, Marshall NE, Okoroha K, Frisch NB, DeSilva SP. The utility of botulinum toxin A in the repair of distal biceps tendon ruptures. Musculoskeletal Surgery. 2017. PMID: 29027640
  • Frisch NB, Wessell NM, Charters MA, Goldstein A, Cann B, Guthrie TS. Early-Stage Chronic Kidney Disease Stage and Hip Fracture Mortality. Journal of Surgical Orthopaedic Advances. 2017. PMID: pending
  • Liu J, Frisch N, Barden R, Rosenberg A, Silverton C, Galante GO. Heterotopic ossification prophylaxis after total hip arthroplasty in high risk patients. Journal of Arthroplasty. 2016. PMID: 27884418
  • Slotkin S, Frisch NB, Roc G, Silverton C. Hemispherical and minimally invasive total hip reamers- a biomechanical analysis of use and design. Arthroplasty Today. October 10, 2016. PMID: 28695186
  • Frisch NB, Lynch J, Banglmaier RF, Silverton CD. The Stability of Dual-Taper Modular Hip Implants: A Biomechanical Analysis Examining the Effect of Impact Direction on Component Stability- Arthroplasty Today. October 7, 2016. PMID: 28695184
  • Mahan C, Frisch NB, Woods T, Parsons TW, Mott MP. Case Report: Ewing's Sarcoma of the Fifth Metacarpal of an Adult Female - JBJS Case Connect, 2016 Dec 14; 6 (4): e95. PMID: 29252749
  • Zang L, Yan M, Mayer T, Johnston B, Less C, Frisch N, Parsons T, Mi Q, Gibson G. The Use of MicroRNA Biomarkers to Distinguish Enchondroma from Low Grade Chondrosarcoma. Connective Tissue Research. 2017 Mar;58(2):155-161. PMID: 27267924
  • Frisch NB, Pepper AM, Jildeh TR, Shaw J, Guthrie ST, Silverton CD. Intraoperative Hypothermia during Surgical Fixation of Hip Fractures - Orthopedics, 2016 Aug 18:1-8. PMID: 27536952
  • Frisch NB, Pepper A, Silverton CD. Intraoperative Temperature Monitoring in Total Hip and Knee Arthroplasty - Orthopedics. 2016 Oct 25:1-8. PMID: 27783839
  • Frisch NB, Nahm N, Khalil JG, Guthrie ST, Charters MA. Short versus Long Cephalomedullary Nail for Pertrochanteric Hip Fractures - Orthopedics, 2016. PMID: 27874910
  • Frisch NB, Wessell NM, Charters MA, Goldstein A, Cann B, Silverton CD. Impact of Body Mass Index on Blood Transfusion in Total Hip and Knee Arthroplasty. Orthopedics. 2016; 39(5):e844-e849. PMID: 26970905
  • Frisch NB, Lynch J, Banglmaier RF, Silverton CD. The Effect of Impact Location on Force Transmission to the Modular Junctions of Dual-Taper Modular Hip Implants - Journal of Arthroplasty, 2016. PMID: 26970905
  • Frisch NB, Charters MA, Sikora-Klak J, Banglmaier RF, Oravec DJ, Silverton CD. Intraoperative Periprosthetic Femur Fracture: A Biomechanical Analysis of Cerlcage Fixation. Journal of Arthroplasty, 2015. PMID: 25765131
  • Charters MA, Frisch NB, Wessell NM, Dobson C, Les CM, Silverton CD. Rivaroxaban versus Enoxaparin for Venous Thromboembolism Prophylaxis after Hip and Knee Arthroplasty. Journal of Arthroplasty, 2015. PMID: 25724111
  • Frisch NB, Wessel NM, Charters MA, Yu S, Jeffries JJ, Silverton CD. Predictors and Complications of Blood Transfusion in Total Hip and Knee Arthroplasty. Journal of Arthroplasty, 2014;29(9Suppl):189-92. PMID: 25007727
  • Nandyala SV, Marquez-Lara, Frisch NB, Park D. The Athletes Spine - Lumbar Herniated Nucleus Pulposus. Oper Tech Sports Med 2013. 21:170-176.
  • Lucier D, Frisch NB, Cohen B, Haas M, Wagner M, Salem D, Fairchild D. Academic Retainer Medicine: An Innovative Business Model for Cross-Subsidizing Primary Care. Academic Medicine 2010 Jun;85(6):959-64. PMID: 20505394
    • Abstracts

      • Frisch, N., Wessell, N., Van Holsbeeck, M., & Silverton, C. (2016). Ultrasound findings in asymptomatic patients with dual taper modular total hip arthroplasty. Bone Joint J 2016, 98-B(SUPP 7), 141.
      • Frisch, N., Scotting, O., Mehran, N., Peters, C., & Silverton, C. KT-1000 analysis of bicruciate retaining total knee arthroplasty. Bone Joint J 2016, 98-B(SUPP 7), 140
      • Frisch, N., Lynch, J., Banglmaier, R., & Silverton, C. Impact direction effects force transmission of modular components in total hip arthroplasty. Bone Joint J 2016, 98-B(SUPP 7), 139.
      • Frisch NB, Sikora-Klak J, Silverton C. Cerclage fixation for cementless total hip arthroplasty complicated by intraoperative
      • Vancouver B1 periprosthetic fractures: A biomechanical analysis. Bone Joint J 2013; 95(SUPP 34): 309.
      • Frisch NB, Charters M, Wessell N, et al. Rivaroxaban versus enoxaparin for venous thromboembolism prophylaxis after hip and knee arthroplasty. Bone Joint J 2013; 95-B(SUPP 34) 60.

Credibility Links

  • American Academy of Orthopaedic Surgeons
  • American Medical Association
  • American Association of Hip and Knee Surgeons
  • Mid-America Orthopaedic Association
  • Michigan Institute for Advanced Surgery Center
  • FAAOS Logo